Shijiazhuang Fourth Pharmaceutical Continues to Innovate: The Antiepileptic Drug Lacosamide Tablets Approved


Time:2021-10-11

On October 11, Shijiazhuang Sihua Pharmaceutical Co., Ltd. received more good news: the company’s lacosamide tablets (50 mg and 100 mg) have been granted a drug registration certificate by the National Medical Products Administration and are deemed to have passed the evaluation of quality and efficacy consistency for generic drugs.

Just after the National Day holiday, on October 11, Shijiazhuang No.4 Pharmaceutical Co., Ltd. received more good news: the company’s lacosamide tablets (50 mg and 100 mg) have been granted drug registration certificates by the National Medical Products Administration and are deemed to have passed the evaluation of bioequivalence and therapeutic equivalence for generic drugs. The approval of this product is of great significance for further enriching the company’s solid dosage form product line.

It is understood that lacosamide is a sodium channel modulator that can regulate the activity of sodium channels, effectively reducing the influx of sodium ions and lowering neuronal excitability, thereby achieving the therapeutic goal of treating epilepsy. It is indicated for monotherapy and combination therapy in patients aged 4 years and older with partial-onset seizures.

Lacosamide is an antiepileptic drug originally developed by UCB Pharma of Belgium, featuring a novel dual mechanism of action. In 2020, global sales of lacosamide reached US$1.656 billion, and the market is currently experiencing rapid growth.

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